LisaKIT Chagas

Microplate test in ELISA format for the detection of antibodies to Trypanosoma cruzi (Chagas' disease) in human sera.

LisaKIT Chagas is a microplate qualitative test for the detection of circulating antibodies to Trypanosoma cruzi (T. cruzi), causative agent of Chagas' disease.

LisaKIT Chagas may be used like confirmatory and/or supplemental serodiagnostic. The test should be used only by professionals.

Chagas' disease, or American trypanosomiasis, is a parasitic disease caused by the hemoflagellate T. cruzi. This disease ranges from southern United States to Northern Argentina and Chile.

The disease is transmitted to humans through the bite wound caused by reduviid bugs, blood transfusions, and in newborns, infection in uterus.

In acute infections, there may be few or no symptoms of the disease. In chronic infections, there may be inflammatory cardiomyopathy, or severe dilation of the oesophagus or colon known as megadisease. The antibodies to T. cruzi appear soon after infection and rise to high levels and may persist, along with infection, for many years, although the parasite is situated inside the cells of the host.

A variety of diagnostic methods have been used, but detection of antibodies to T. cruzi antigens remains the strongest method to diagnose infection. Seropositivity is frequently established in the clinical laboratory using techniques as ELISA, due to its easy-to-use format, excellent sensitivity and specificity and the possibility of automation.

	Technique	Sample	Promotional Sheet	CE Decl.	Instruct.	Technical Reports
LisaKIT Chagas	ELISA	serum		N/A		N/A