One-step immunochromatographic test for a qualitative detection is stool samples of Clostridium difficile toxin A (TcdA) and toxin B (TcdB) in two separate bands.
A positive band of either toxin is a sign of an underlying Clostridium difficile infection (CDI), which should attract the attention of the physician.
C.difficile produces two different toxins that constitute the essential virulence factors for CDI induction. Recent investigations have proven that each of the two alone will induce disease in hamsters.
C.difficile infection is considered responsible for approximately 25% of the diarrhoea incidents related to the consumption of antibiotics such as clindamycin, second and third generation cephalosporins, gyrase-Inhibitors, ampicillin or amoxicillin.
In addition to the diarrhoea symptoms, the disease can lead to pseudo-membranous colitis (PMC), requiring urgent treatment with antibiotics effective against C.difficile and which, without treatment, may severely compromise the life of the patient.
| Technique | Sample | Promotional Sheet |
CE Decl. | Instruct. | Technical Reports |
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|---|---|---|---|---|---|---|
| 2A-Bdiff | Immunochromatography | stool | ![]() |
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